@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .

nalt:47442_def
  rdf:value "Mutagénesis en la que la mutación es causada por la introducción de secuencias de ADN extraño en un gen. Esto puede ocurrir espontáneamente in vivo o se puede introducir experimentalmente in vitro. Se puede insertar ADN proviral a un proto oncógeno en forma directa o adyacente. La inserción del provirus puede causar mutaciones interrumpiendo las secuencias de codificación o los elementos reguladores, o causar expresiones no reguladas del proto oncógeno, lo cual produce formación de tumores."@es, "Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene or extragenic sequence. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA insertions into or adjacent to a cellular proto-oncogene can interrupt genetic translation of the coding sequences or interfere with recognition of regulatory elements and cause unregulated expression of the proto-oncogene resulting in tumor formation."@en ;
  dc:source "Medical Subject Headings 2012" ;
  a <https://lod.nal.usda.gov/naltv#Definition> .

nalt:10457
  skos:prefLabel "mutagénesis"@es, "mutagenesis"@en ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  skos:narrower nalt:47442 .

<https://lod.nal.usda.gov/nalt-core>
  rdfs:label "NALT Core"@es, "NALT Core"@en ;
  a skos:ConceptScheme .

<https://lod.nal.usda.gov/naltv#Topic>
  rdfs:label "Topic"@en ;
  a owl:Class .

nalt:52801
  skos:prefLabel "secuencias repetitivas"@es, "repetitive sequences"@en ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  skos:related nalt:47442 .

nalt:254147
  skos:prefLabel "secuencias repetitivas dispersas"@es, "interspersed repetitive sequences"@en ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  skos:related nalt:47442 .

nalt:47442
  dc:modified "2015-05-29"^^xsd:date ;
  skos:exactMatch <http://id.cabi.org/cabt/61165>, <http://id.agrisemantics.org/gacs/C10953> ;
  skos:hiddenLabel "insertion mutagenesis"@en, "insertional-mutagenesis"@en, "soilsite-directed mutagenesis"@en ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  skos:inScheme <https://lod.nal.usda.gov/nalt-core>, <https://lod.nal.usda.gov/nalt> ;
  skos:prefLabel "mutagénesis insercional"@es, "insertional mutagenesis"@en ;
  skos:broader nalt:10457 ;
  skos:related nalt:52801, nalt:254147 ;
  dc:created "2006-01-19"^^xsd:date ;
  ns0:marc001 "19506" ;
  skos:definition nalt:47442_def .