@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

nalt:131695
  skos:definition nalt:131695_def ;
  dc:created "2009-08-19"^^xsd:date ;
  skos:prefLabel "tacrolimus"@en, "tacrolimo"@es ;
  dc:modified "2013-09-05"^^xsd:date ;
  ns0:marc001 "58258" ;
  skos:closeMatch <http://id.loc.gov/authorities/subjects/sh94005977> ;
  a ns0:Chemical, skos:Concept ;
  skos:broader nalt:8121 ;
  skos:inScheme <https://lod.nal.usda.gov/nalt> ;
  skos:related nalt:20596 .

nalt:131695_def
  rdf:value "Macrólido de actividad inmunosupresora aislado del cultivo de una cepa de Streptomyces tsukubaensis que tiene una fuerte actividad inmunosupresora in vivo y previene la activación de los linfocitos T en respuesta a la estimulación antigénica o mitogénica in vitro."@es, "A macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro."@en ;
  dc:source "Medical Subject Headings" ;
  a ns0:Definition .

ns0:Chemical
  rdfs:label "Chemical"@en ;
  a owl:Class .

nalt:20596
  skos:prefLabel "agentes inmunosupresores"@es, "immunosuppressive agents"@en ;
  a ns0:Chemical, skos:Concept ;
  skos:related nalt:131695 .

<https://lod.nal.usda.gov/nalt>
  rdfs:label "NALT Full"@en ;
  a skos:ConceptScheme .

nalt:8121
  skos:prefLabel "macrolidas"@es, "macrolides"@en ;
  a ns0:Chemical, skos:Concept ;
  skos:narrower nalt:131695 .