@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .

nalt:18969
  skos:prefLabel "trastornos leucocíticos"@es, "leukocyte disorders"@en ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  skos:narrower nalt:17877 .

nalt:17877_def
  rdf:value "Enfermedad hereditaria recesiva autosómica que afecta a terneros Holstein. Los especimenes homocigóticos mueren debido a susceptibilidad extrema a infecciones, causada por la incapacidad de los leucocitos de pasar del torrente sanguíneo al tejido infectado. Esta incapacidad la causa la falta de proteína de adhesión integrina beta 2 en la superficie de los linfocitos debido a mutación de dos puntos en el gen CD 18."@es, "An autosomal recessive hereditary disease affecting young Holstein calves. Homozygous individuals die from extreme susceptibility to infection, caused by an inability of leukocytes to pass from the blood stream into infected tissue. This inability is due to the lack of beta-2 integrin adhesion protein on the surface of the white blood cells due to two point mutations in the CD18 gene."@en ;
  dc:source "NAL Thesaurus Staff" ;
  a <https://lod.nal.usda.gov/naltv#Definition> .

<https://lod.nal.usda.gov/naltv#Topic>
  rdfs:label "Topic"@en ;
  a owl:Class .

nalt:18968
  skos:prefLabel "trastornos genéticos"@es, "genetic disorders"@en ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  skos:narrower nalt:17877 .

nalt:17877
  skos:prefLabel "bovine leukocyte adhesion deficiency"@en, "deficiencia de adhesión de leucocitos en bovinos"@es ;
  skos:broader nalt:9125, nalt:18969, nalt:18968 ;
  a skos:Concept, <https://lod.nal.usda.gov/naltv#Topic> ;
  skos:definition nalt:17877_def ;
  skos:hiddenLabel "bovine-leukocyte-adhesion-deficiency"@en ;
  skos:inScheme <https://lod.nal.usda.gov/nalt> ;
  dc:modified "2012-11-30"^^xsd:date ;
  skos:altLabel "BLAD (animal disease)"@en ;
  dc:created "2006-01-19"^^xsd:date ;
  ns0:marc001 "5580" .

<https://lod.nal.usda.gov/nalt>
  rdfs:label "NALT Full"@en ;
  a skos:ConceptScheme .

nalt:9125
  skos:prefLabel "enfermedades del ganado vacuno"@es, "cattle diseases"@en ;
  a ns0:Topic, skos:Concept ;
  skos:narrower nalt:17877 .