@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .

nalt:261145
  skos:prefLabel "modelos biológicos"@es, "biological models"@en ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  skos:narrower nalt:19688486 .

nalt:19688486_def
  rdf:value "Método que integra datos sobre fármacos (sustancias) y sistemas (fisiología) en un marco de modelización matemática para efectuar predicciones en ámbitos como la exposición a toxinas y el desarrollo de medicamentos."@es, "A method that integrates drug (substance) and system (physiology) data into a mathematical modeling framework for prediction in areas such as toxin exposure and drug development."@en ;
  dc:source "Based upon Program of physiologically-based pharmacokinetic and pharmacodynamic modeling (PBPK Program), September 4, 2018, U.S. Food and Drug Administration website, Accessed September 21, 2022." ;
  a <https://lod.nal.usda.gov/naltv#Definition> .

<https://lod.nal.usda.gov/nalt>
  rdfs:label "NALT Full"@en ;
  a skos:ConceptScheme .

nalt:19688486
  dc:created "2023-04-03"^^xsd:date ;
  skos:prefLabel "physiology based pharmacodynamic models (PBPD)"@en, "modelos farmacodinámicos con base fisiológica (PBPD)"@es ;
  skos:definition nalt:19688486_def ;
  skos:inScheme <https://lod.nal.usda.gov/nalt-awic>, <https://lod.nal.usda.gov/nalt> ;
  skos:broader nalt:261145 ;
  a skos:Concept ;
  dc:modified "2024-05-04"^^xsd:date ;
  ns0:marc001 "19688486" .