@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

nalt:21100
  skos:hiddenLabel "Ca(2+) channel blockers"@en, "Ca2+ channel blockers"@en, "Ca2+ channel blocker"@en, "calcium channel blocker"@en, "calcium-channel-blockers"@en, "Ca-channel blocker"@en, "Ca-channel blockers"@en, "Ca(2+) channel blocker"@en ;
  skos:closeMatch <http://id.loc.gov/authorities/subjects/sh85018769> ;
  skos:prefLabel "bloqueadores de los canales de calcio"@es, "calcium channel blockers"@en ;
  dc:created "2006-01-19"^^xsd:date ;
  skos:inScheme <https://lod.nal.usda.gov/nalt> ;
  ns0:marc001 "6382" ;
  a skos:Concept, ns0:Chemical ;
  skos:related nalt:21102, nalt:286434, nalt:264312 ;
  skos:narrower nalt:21101 ;
  dc:modified "2016-08-26"^^xsd:date ;
  skos:definition nalt:21100_def ;
  skos:broader nalt:10385 .

nalt:286434
  skos:prefLabel "conotoxinas"@es, "conotoxins"@en ;
  a ns0:Topic, skos:Concept ;
  skos:related nalt:21100 .

nalt:21100_def
  rdf:value "Tipo de medicamentos que actúan por inhibición selectiva del flujo de calcio entrante a través de las membranas celulares o en la liberación y unión de calcio en depósitos intracelulares. Puesto que inducen la relajación vascular y de la musculatura lisa, se utilizan en la terapia medicamentosa de la hipertensión y de los espasmos cerebrovasculares como agentes protectores del miocardio, y en la relajación de espasmos uterinos."@es, "A class of drugs that act by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools. Since they are inducers of vascular and other smooth muscle relaxation, they are used in the drug therapy of hypertension and cerebrovascular spasms, as myocardial protective agents, and in the relaxation of uterine spasms."@en ;
  dc:source "Medical Subject Headings 2012" ;
  a ns0:Definition .

nalt:264312
  skos:prefLabel "rojo de rutenio"@es, "ruthenium red"@en ;
  a ns0:Chemical, skos:Concept ;
  skos:related nalt:21100 .

nalt:21101
  skos:prefLabel "verapamil"@es, "verapamil"@en ;
  a ns0:Chemical, skos:Concept ;
  skos:broader nalt:21100 .

ns0:Chemical
  rdfs:label "Chemical"@en ;
  a owl:Class .

nalt:10385
  skos:prefLabel "agentes cardiovasculares"@es, "cardiovascular agents"@en ;
  a ns0:Chemical, skos:Concept ;
  skos:narrower nalt:21100 .

<https://lod.nal.usda.gov/nalt>
  rdfs:label "NALT Full"@en ;
  a skos:ConceptScheme .

nalt:21102
  skos:prefLabel "canales de calcio"@es, "calcium channels"@en ;
  a ns0:Chemical, skos:Concept ;
  skos:related nalt:21100 .