@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .

nalt:2996
  skos:prefLabel "inmunidad"@es, "immunity"@en ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  skos:narrower nalt:217636 .

<https://lod.nal.usda.gov/naltv#Topic>
  rdfs:label "Topic"@en ;
  a owl:Class .

nalt:217636
  skos:prefLabel "afinidad del anticuerpo"@es, "antibody affinity"@en ;
  skos:inScheme <https://lod.nal.usda.gov/nalt> ;
  skos:hiddenLabel "antibody-affinity"@en ;
  skos:altLabel "antibody avidity"@en ;
  dc:created "2014-06-04"^^xsd:date ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  dc:modified "2017-04-12"^^xsd:date ;
  skos:related nalt:297821 ;
  skos:broader nalt:2996 ;
  skos:definition nalt:217636_def ;
  ns0:marc001 "63141" .

nalt:217636_def
  rdf:value "Medida de la fuerza de unión entre un anticuerpo y un hapteno o un determinante antigénico simple. Depende de la proximidad del ajuste estereoquímico entre los sitios de combinación del anticuerpo y los determinantes antigénicos, del tamaño del área de contacto entre ellos y de la distribución de los grupos cargados e hidrofóbicos. Incluye el concepto de “avidez”, que se refiere a la fuerza de la unión antígeno-anticuerpo, luego de la formación de complejos reversibles."@es, "A measure of the binding strength between antibody and a simple hapten or antigen determinant. It depends on the closeness of stereochemical fit between antibody combining sites and antigen determinants, on the size of the area of contact between them, and on the distribution of charged and hydrophobic groups. It includes the concept of \"avidity,\" which refers to the strength of the antigen-antibody bond after formation of reversible complexes."@en ;
  dc:source "Medical Subject Headings 2014" ;
  a ns0:Definition .

<https://lod.nal.usda.gov/nalt>
  rdfs:label "NALT Full"@en ;
  a skos:ConceptScheme .

nalt:297821
  skos:prefLabel "ingeniería de anticuerpos"@es, "antibody engineering"@en ;
  a ns0:Topic, skos:Concept ;
  skos:related nalt:217636 .