@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

nalt:146200
  skos:prefLabel "receptor de la proteína-tirosina quinasa"@es, "receptor protein-tyrosine kinase"@en ;
  a <https://lod.nal.usda.gov/naltv#Chemical>, skos:Concept ;
  skos:narrower nalt:222856 .

<https://lod.nal.usda.gov/naltv#Chemical>
  rdfs:label "Chemical"@en ;
  a owl:Class .

nalt:222856_def
  rdf:value "Receptor de la proteína tirosina quinasa de la superficie celular sobreexpresado en un número significativo de adenocarcinomas. Presenta una gran homología y puede heterodimerizar con el receptor de factor de crecimiento epidérmico y los receptores erbB-3 y erbB-4. La activación del receptor erbB-2 tiene lugar durante la formación del heterodímero con miembros de la familia de un receptor erbB unido al ligando."@es, "A cell surface protein-tyrosine kinase receptor that is found to be overexpressed in a significant number of adenocarcinomas. It has extensive homology to and can heterodimerize with the EGF receptor (epidermal growth factor receptor), the erbB-3 receptor and the erbB-4 receptor. Activation of the erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB receptor family members."@en ;
  dc:source "Medical Subject Headings 2014" ;
  a <https://lod.nal.usda.gov/naltv#Definition> .

nalt:222856
  skos:altLabel "erbB-2 receptor protein-tyrosine kinase"@en, "proto-oncogene protein HER-2"@en, "HER-2 proto-oncogene protein"@en, "human epidermal growth factor receptor-2"@en, "c-erbB-2 protein"@en, "neu receptor"@en, "c-neu proto-oncogene protein"@en, "erbB-2 proto-oncogene protein"@en, "proto-oncogene protein c-neu"@en, "c-erbB2 receptor"@en, "proto-oncogene proteins c-erbB-2"@en ;
  skos:prefLabel "erbB-2 receptor"@en, "receptor erbB-2"@es ;
  skos:hiddenLabel "human epidermal growth factor receptor 2"@en, "erbB-2-receptor"@en ;
  ns0:marc001 "66506" ;
  a skos:Concept, ns0:Chemical ;
  skos:definition nalt:222856_def ;
  dc:modified "2015-12-10"^^xsd:date ;
  skos:broader nalt:146200 ;
  skos:inScheme <https://lod.nal.usda.gov/nalt> ;
  dc:created "2014-07-25"^^xsd:date .

<https://lod.nal.usda.gov/nalt>
  rdfs:label "NALT Full"@en ;
  a skos:ConceptScheme .