@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

nalt:232248_def
  rdf:value "Sistemas de regularización de la señalización que controlan la progresión a través del ciclo celular. Aseguran que la célula haya completado, en el orden correcto y sin errores, todos los procesos requeridos para replicar el genoma y el citoplasma y los divide en partes iguales entre dos células hijas. Si las células no han completado estos procesos o el ambiente carece de los nutrientes y las hormonas de crecimiento para proseguir, las células quedan limitadas o “detenidas” hasta que los procesos sean completados y las condiciones de crecimiento sean las idóneas."@es, "Regulatory signaling systems that control the progression through the cell cycle. They ensure that the cell has completed, in the correct order and without mistakes, all the processes required to replicate the genome and cytoplasm, and divide them equally between two daughter cells. If cells sense they have not completed these processes or that the environment does not have the nutrients and growth hormones in place to proceed, then the cells are restrained (or \"arrested\") until the processes are completed and growth conditions are suitable."@en ;
  dc:source "Medical Subject Headings 2015" ;
  a <https://lod.nal.usda.gov/naltv#Definition> .

nalt:8512
  skos:prefLabel "división celular"@es, "cell division"@en ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  skos:related nalt:232248 .

nalt:23357
  skos:prefLabel "proliferación celular"@es, "cell proliferation"@en ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  skos:related nalt:232248 .

nalt:23397
  skos:prefLabel "crecimiento celular"@es, "cell growth"@en ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  skos:related nalt:232248 .

nalt:34962
  skos:prefLabel "retardo del crecimiento"@es, "growth retardation"@en ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  skos:related nalt:232248 .

nalt:314424
  skos:prefLabel "mitógenos"@es, "mitogens"@en ;
  a <https://lod.nal.usda.gov/naltv#Chemical>, skos:Concept ;
  skos:related nalt:232248 .

<https://lod.nal.usda.gov/naltv#Topic>
  rdfs:label "Topic"@en ;
  a owl:Class .

nalt:232248
  skos:related nalt:8512, nalt:316636, nalt:34962, nalt:23397, nalt:314424, nalt:34224, nalt:11242, nalt:23357 ;
  ns0:marc001 "64657" ;
  skos:hiddenLabel "cell-proliferation arrests"@en, "cell cycle checkpoint"@en, "cell-cycle checkpoint"@en, "cell-cycle arrest"@en, "G1 cell cycle arrest"@en, "cell-cycle-checkpoints"@en, "cell-growth arrest"@en, "phase checkpoints"@en, "cell cycle-checkpoint"@en, "cell-cycle checkpoints"@en, "cell-proliferation arrest"@en, "cell-cycle-checkpoint"@en, "cell growth arrest"@en, "cell proliferation arrests"@en, "cell proliferation arrest"@en ;
  skos:broader nalt:23382 ;
  skos:inScheme <https://lod.nal.usda.gov/nalt> ;
  skos:altLabel "cell cycle arrest"@en ;
  skos:prefLabel "puntos de control del ciclo celular"@es, "cell cycle checkpoints"@en ;
  a ns0:Topic, skos:Concept ;
  dc:created "2014-10-10"^^xsd:date ;
  skos:definition nalt:232248_def ;
  dc:modified "2018-05-09"^^xsd:date .

<https://lod.nal.usda.gov/nalt>
  rdfs:label "NALT Full"@en ;
  a skos:ConceptScheme .

nalt:23382
  skos:prefLabel "ciclo celular"@es, "cell cycle"@en ;
  a ns0:Topic, skos:Concept ;
  skos:narrower nalt:232248 .

nalt:34224
  skos:prefLabel "replicación de ADN"@es, "DNA replication"@en ;
  a ns0:Topic, skos:Concept ;
  skos:related nalt:232248 .

nalt:11242
  skos:prefLabel "apoptosis"@es, "apoptosis"@en ;
  a ns0:Topic, skos:Concept ;
  skos:related nalt:232248 .

nalt:316636
  skos:prefLabel "agentes antimitóticos"@es, "antimitotic agents"@en ;
  a ns0:Chemical, skos:Concept ;
  skos:related nalt:232248 .

