@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .

nalt:243281_def
  rdf:value "La citosina pequeña inducible A13, inducida por la IL-1 y el TNF-alfa y ampliamente expresada y codificada por el gen CCL13 humano (familia de intercrinas beta) y el 98-aa 11-kD (precursor), constituye un factor quimiotáctico secretado de monocitos, linfocitos, basófilos y eosinófilos que da señales mediante los receptores CCR2B y CCR3 e interviene en procesos inmunorreguladores e inflamatorios. La proteína puede enlazar la heparina y las isoformas MCP-4, (LA) MCP-4 y (FNPQGLA) MCP-4. El gen CCL13 puede intervenir en el desarrollo de la aterosclerosis."@es, "Induced by IL-1 and TNF-alpha, widely expressed, and encoded by human CCL13 Gene (Intercrine Beta Family), 98-aa 11-kD (precursor) Small Inducible Cytokine A13 is a secreted chemotactic factor for monocytes, lymphocytes, basophils, and eosinophils that signals through CCR2B and CCR3 receptors and is involved in immunoregulatory and inflammatory processes. The protein can bind heparin and isoforms MCP-4, (LA) MCP-4, and (FNPQGLA) MCP-4 exist. CCL13 may be involved in atherosclerosis."@en ;
  dc:source "National Cancer Institute Thesaurus" ;
  a <https://lod.nal.usda.gov/naltv#Definition> .

<https://lod.nal.usda.gov/naltv#Chemical>
  rdfs:label "Chemical"@en ;
  a owl:Class .

nalt:243410
  skos:prefLabel "receptor CCR2"@es, "CCR2 receptor"@en ;
  a <https://lod.nal.usda.gov/naltv#Chemical>, skos:Concept ;
  skos:related nalt:243281 .

nalt:243435
  skos:prefLabel "receptor CCR3"@es, "CCR3 receptor"@en ;
  a <https://lod.nal.usda.gov/naltv#Chemical>, skos:Concept ;
  skos:related nalt:243281 .

nalt:243281
  dc:created "2015-03-10"^^xsd:date ;
  skos:inScheme <https://lod.nal.usda.gov/nalt> ;
  skos:hiddenLabel "chemokine-CCL13"@en ;
  skos:prefLabel "quimiocina CCL13"@es, "chemokine CCL13"@en ;
  a <https://lod.nal.usda.gov/naltv#Chemical>, skos:Concept ;
  skos:altLabel "CC chemokine ligand 13"@en, "SCYL1 chemokine"@en, "new CC chemokine-1"@en, "small inducible cytokine A13"@en, "monocyte chemoattractant protein-4"@en, "MCP4 chemokine"@en, "CCL13 chemokine"@en, "MCP-4 chemokine"@en, "chemokine (C-C motif) ligand 13"@en, "SCYA13 chemokine"@en, "NCC-1 chemokine"@en, "monocyte chemotactic protein-4"@en ;
  skos:related nalt:243435, nalt:243410 ;
  skos:definition nalt:243281_def ;
  dc:modified "2015-11-16"^^xsd:date ;
  skos:broader nalt:236769 ;
  ns0:marc001 "64858" .

<https://lod.nal.usda.gov/nalt>
  rdfs:label "NALT Full"@en ;
  a skos:ConceptScheme .

nalt:236769
  skos:prefLabel "proteínas quimioatrayentes de monocitos"@es, "monocyte chemoattractant proteins"@en ;
  a ns0:Chemical, skos:Concept ;
  skos:narrower nalt:243281 .

