@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

nalt:236677
  skos:prefLabel "quimiocina CCL1"@es, "chemokine CCL1"@en ;
  a <https://lod.nal.usda.gov/naltv#Chemical>, skos:Concept ;
  skos:related nalt:243493 .

nalt:243493
  skos:prefLabel "CCR8 receptor"@en, "receptor CCR8"@es ;
  dc:modified "2015-11-16"^^xsd:date ;
  skos:altLabel "CDw198 antigen"@en, "chemokine receptor CLR-L1"@en, "CC-CKR8 receptor"@en, "chemokine receptor CKRL1"@en, "CKR8 receptor"@en, "chemokine receptor TER1"@en, "chemokine (C-C) receptor 8"@en, "GPR-CY6 (G-protein coupled receptor-CY6)"@en, "C-C chemokine receptor type 8"@en, "chemokine (C-C motif) receptor 8"@en, "CC chemokine receptor 8"@en ;
  skos:related nalt:236677 ;
  ns0:marc001 "64636" ;
  skos:inScheme <https://lod.nal.usda.gov/nalt> ;
  skos:definition nalt:243493_def ;
  skos:broader nalt:243407 ;
  skos:hiddenLabel "CDw198 receptors"@en, "CCR8-receptor"@en, "CCR8 receptors"@en ;
  a skos:Concept, ns0:Chemical ;
  dc:created "2015-03-10"^^xsd:date .

nalt:243493_def
  rdf:value "Proteína receptora que se expresa preferentemente en el timo, cuyos ligandos identificados son la citosina I-309 con activación regulada por el timo (TARC) y la proteína inflamatoria de macrófagos 1 beta (MIP-1 beta). Desempeña una función en la regulación de la quimiotaxis de monocitos y la apoptosis de células tímicas. Más específicamente, puede contribuir a la colocación adecuada de las células T activadas en los sitios de exposición al antígeno y en las zonas especializadas de los tejidos linfoides."@es, "This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues."@en ;
  dc:source "National Center for Biotechnology Information" ;
  a ns0:Definition .

ns0:Chemical
  rdfs:label "Chemical"@en ;
  a owl:Class .

nalt:243407
  skos:prefLabel "receptores de quimiocinas"@es, "chemokine receptors"@en ;
  a ns0:Chemical, skos:Concept ;
  skos:narrower nalt:243493 .

<https://lod.nal.usda.gov/nalt>
  rdfs:label "NALT Full"@en ;
  a skos:ConceptScheme .

