@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

nalt:253695
  skos:prefLabel "meropenem"@es, "meropenem"@en ;
  a <https://lod.nal.usda.gov/naltv#Chemical>, skos:Concept ;
  skos:broader nalt:253696 .

nalt:253696_def
  rdf:value "Antibióticos betalactámicos que difieren de las penicilinas en que un carbono reemplaza al átomo de azufre de la tiazolidina, por lo que este último se convierte en el primer átomo en la cadena lateral. Son químicamente inestables; sin embargo, son de muy amplio espectro antibacteriano. Se propone su uso y el de sus derivados más estables en combinación con inhibidores enzimáticos."@es, "Beta-lactam antibiotics that differ from penicillins in having the thiazolidine sulfur atom replaced by carbon, the sulfur then becoming the first atom in the side chain. They are unstable chemically, but have a very broad antibacterial spectrum. Thienamycin and its more stable derivatives are proposed for use in combinations with enzyme inhibitors."@en ;
  dc:source "Medical Subject Headings 2015" ;
  a <https://lod.nal.usda.gov/naltv#Definition> .

nalt:148699
  skos:prefLabel "carbapenemes"@es, "carbapenems"@en ;
  a <https://lod.nal.usda.gov/naltv#Chemical>, skos:Concept ;
  skos:narrower nalt:253696 .

nalt:253696
  dc:modified "2015-11-16"^^xsd:date ;
  skos:narrower nalt:253695 ;
  dc:created "2015-05-26"^^xsd:date ;
  skos:inScheme <https://lod.nal.usda.gov/nalt> ;
  skos:related nalt:8044 ;
  skos:hiddenLabel "thienamycins"@en ;
  a <https://lod.nal.usda.gov/naltv#Chemical>, skos:Concept ;
  skos:prefLabel "thienamycin"@en, "tienamicinas"@es ;
  ns0:marc001 "74195" ;
  skos:definition nalt:253696_def ;
  skos:broader nalt:148699 .

ns0:Chemical
  rdfs:label "Chemical"@en ;
  a owl:Class .

nalt:8044
  skos:prefLabel "penicilinas"@es, "penicillins"@en ;
  a ns0:Chemical, skos:Concept ;
  skos:related nalt:253696 .

<https://lod.nal.usda.gov/nalt>
  rdfs:label "NALT Full"@en ;
  a skos:ConceptScheme .