@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .

nalt:271233
  skos:hiddenLabel "gamma-aminobutyric acid receptor"@en, "GABA receptor"@en, "GABA-B receptors"@en, "GABA-A receptor"@en, "gamma-aminobutyric-acid-receptors"@en, "GABA-B receptor"@en, "GABA-A receptors"@en ;
  a skos:Concept, <https://lod.nal.usda.gov/naltv#Chemical> ;
  ns0:marc001 "76964" ;
  skos:prefLabel "receptores de ácido gama-aminobutírico"@es, "gamma-aminobutyric acid receptors"@en ;
  skos:altLabel "GABA receptors"@en ;
  skos:broader nalt:223311 ;
  dc:created "2016-01-29"^^xsd:date ;
  skos:related nalt:22289 ;
  skos:definition nalt:271233_def ;
  skos:inScheme <https://lod.nal.usda.gov/nalt> ;
  dc:modified "2017-07-06"^^xsd:date .

ns0:Chemical
  rdfs:label "Chemical"@en ;
  a owl:Class .

nalt:271233_def
  rdf:value "Proteínas de la superficie celular que se unen con gran afinidad al ácido gamma-aminobutírico (GABA) y que producen cambios que influyen en el comportamiento de las células. Los receptores de GABA-A controlan los canales de cloruro formados por el propio complejo del receptor. Estos son bloqueados por la bicuculina y suelen presentar sitios moduladores sensibles a las benzodiazepinas y a los barbitúricos. Los receptores de GABA-B actúan a través de las proteínas G en varios sistemas efectores, son insensibles a la bicuculina y presentan una alta afinidad al L-baclofeno."@es, "Cell-surface proteins that bind gamma-aminobutyric acid with high affinity and trigger changes that influence the behavior of cells. GABA-A receptors control chloride channels formed by the receptor complex itself. They are blocked by bicuculline and usually have modulatory sites sensitive to benzodiazepines and barbiturates. GABA-B receptors act through G-proteins on several effector systems, are insensitive to bicuculline, and have a high affinity for L-baclofen."@en ;
  dc:source "Medical Subject Headings 2016" ;
  a ns0:Definition .

nalt:22289
  skos:prefLabel "ácido gama-aminobutírico"@es, "gamma-aminobutyric acid"@en ;
  a ns0:Chemical, skos:Concept ;
  skos:related nalt:271233 .

<https://lod.nal.usda.gov/nalt>
  rdfs:label "NALT Full"@en ;
  a skos:ConceptScheme .

nalt:223311
  skos:prefLabel "receptores acoplados a proteínas G"@es, "G-protein coupled receptors"@en ;
  a ns0:Chemical, skos:Concept ;
  skos:narrower nalt:271233 .