@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

nalt:278705
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  skos:hiddenLabel "null mutations"@en, "loss-of-function"@en, "amorphic mutations"@en ;
  skos:related nalt:6537, nalt:278704, nalt:324466 ;
  skos:prefLabel "loss-of-function mutation"@en, "mutación de pérdida de función"@es ;
  skos:inScheme <https://lod.nal.usda.gov/nalt> ;
  skos:altLabel "amorphic mutation"@en, "null mutation"@en ;
  ns0:marc001 "77584" ;
  skos:definition nalt:278705_def ;
  skos:broader nalt:7777 ;
  dc:created "2016-05-23"^^xsd:date ;
  dc:modified "2018-09-18"^^xsd:date .

nalt:278705_def
  rdf:value "Tipo de mutación en la que el producto del gen alterado carece de la función molecular del gen en estado natural."@es, "A type of mutation in which the altered gene product lacks the molecular function of the wild-type gene."@en ;
  dc:source "National Cancer Institute, eMICE, Glossary" ;
  a ns0:Definition .

nalt:7777
  skos:prefLabel "mutación"@es, "mutation"@en ;
  a ns0:Topic, skos:Concept ;
  skos:narrower nalt:278705 .

nalt:6537
  skos:prefLabel "alelos"@es, "alleles"@en ;
  a ns0:Topic, skos:Concept ;
  skos:related nalt:278705 .

ns0:Topic
  rdfs:label "Topic"@en ;
  a owl:Class .

nalt:278704
  skos:prefLabel "mutación de ganancia de función"@es, "gain-of-function mutation"@en ;
  a ns0:Topic, skos:Concept ;
  skos:related nalt:278705 .

<https://lod.nal.usda.gov/nalt>
  rdfs:label "NALT Full"@en ;
  a skos:ConceptScheme .

nalt:324466
  skos:prefLabel "haploinsuficiencia"@es, "haploinsufficiency"@en ;
  a ns0:Topic, skos:Concept ;
  skos:related nalt:278705 .