@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .

<https://lod.nal.usda.gov/naltv#Chemical>
  rdfs:label "Chemical"@en ;
  a owl:Class .

nalt:28007
  skos:broader nalt:28005 ;
  dc:modified "2016-05-20"^^xsd:date ;
  skos:inScheme <https://lod.nal.usda.gov/nalt> ;
  skos:prefLabel "macrophage colony-stimulating factor"@en, "factor de estimulación de colonias de macrófagos"@es ;
  a skos:Concept, <https://lod.nal.usda.gov/naltv#Chemical> ;
  ns0:marc001 "22143" ;
  skos:altLabel "colony stimulating factor 1"@en, "colony stimulating factor-1"@en ;
  skos:hiddenLabel "macrophage-colony stimulating factors"@en, "macrophage-colony-stimulating-factor"@en, "macrophage colony stimulating factors"@en, "macrophage-colony stimulating factor"@en ;
  dc:created "2006-01-19"^^xsd:date ;
  skos:definition nalt:28007_def .

nalt:28007_def
  rdf:value "Factor de estimulación de colonias de fagocitos mononucleares (M-CSF) sintetizado por células mesenquimatosas. Estimula la supervivencia, la proliferación y la diferenciación de las células hematopoyéticas de la serie de monocitos-macrófagos. Constituye un dímero glucoproteico con enlaces disulfuro y un PM de 70 kDa. Se une a un receptor específico de alta afinidad (receptor de factores de estimulación de colonias de fagocitos)."@es, "A mononuclear phagocyte colony-stimulating factor (M-CSF) synthesized by mesenchymal cells. The compound stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series. M-CSF is a disulfide-bonded glycoprotein dimer with a MW of 70 kDa. It binds to a specific high affinity receptor (macrophage colony-stimulating factor receptor)."@en ;
  dc:source "Medical Subject Headings 2015" ;
  a ns0:Definition .

<https://lod.nal.usda.gov/nalt>
  rdfs:label "NALT Full"@en ;
  a skos:ConceptScheme .

nalt:28005
  skos:prefLabel "factores estimulantes de colonias"@es, "colony-stimulating factors"@en ;
  a ns0:Chemical, skos:Concept ;
  skos:narrower nalt:28007 .