@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .

nalt:286434
  skos:hiddenLabel "a-conotoxins"@en, "conotoxin"@en, "o-conotoxin"@en, "alpha-conotoxin"@en, "cone snail venoms"@en, "o-conotoxins"@en, "a-conotoxin"@en, "mu-conotoxin"@en, "cone snail venom"@en, "Conus venom"@en ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  skos:related nalt:2518, nalt:21102, nalt:639, nalt:21100, nalt:285911 ;
  skos:prefLabel "conotoxins"@en, "conotoxinas"@es ;
  skos:altLabel "alpha-conotoxins"@en, "omega-conotoxins"@en, "mu-conotoxins"@en ;
  skos:definition nalt:286434_def ;
  skos:inScheme <https://lod.nal.usda.gov/nalt> ;
  ns0:marc001 "76182" ;
  dc:created "2016-08-26"^^xsd:date ;
  skos:broader nalt:10560 ;
  dc:modified "2017-07-06"^^xsd:date .

nalt:21100
  skos:prefLabel "bloqueadores de los canales de calcio"@es, "calcium channel blockers"@en ;
  a ns0:Chemical, skos:Concept ;
  skos:related nalt:286434 .

nalt:285911
  skos:prefLabel "Conus"@es, "Conus"@en ;
  a ns0:Organism, skos:Concept ;
  skos:related nalt:286434 .

nalt:639
  skos:prefLabel "moluscos"@es, "molluscs"@en ;
  a ns0:Organism, skos:Concept ;
  skos:related nalt:286434 .

ns0:Topic
  rdfs:label "Topic"@en ;
  a owl:Class .

nalt:10560
  skos:prefLabel "venenos"@es, "venoms"@en ;
  a ns0:Topic, skos:Concept ;
  skos:narrower nalt:286434 .

nalt:286434_def
  rdf:value "Neurotoxinas peptídicas de los caracoles marinos del género Conus que cazan peces. Contienen de 13 a 29 aminoácidos muy básicos que forman numerosos puentes disulfuro. Existen tres tipos de conotoxinas: omega-, alfa- y mu-. Las omega-conotoxinas inhiben la entrada de calcio activada por voltaje en la membrana presináptica y, por consiguiente, la liberación de acetilcolina. Las alfa-conotoxinas inhiben al receptor postsináptico de acetilcolina. Las mu-conotoxinas evitan la generación de potenciales de acción muscular."@es, "Peptide neurotoxins from the marine fish-hunting snails of the genus Conus. They contain 13 to 29 amino acids which are strongly basic and are highly cross-linked by disulfide bonds. There are three types of conotoxins, omega-, alpha-, and mu-. Omega-conotoxins inhibit voltage-activated entry of calcium into the presynaptic membrane and therefore the release of acetylcholine. Alpha-conotoxins inhibit the postsynaptic acetylcholine receptor. Mu-conotoxins prevent the generation of muscle action potentials."@en ;
  dc:source "Medical Subject Headings 2016" ;
  a ns0:Definition .

<https://lod.nal.usda.gov/nalt>
  rdfs:label "NALT Full"@en ;
  a skos:ConceptScheme .

nalt:21102
  skos:prefLabel "canales de calcio"@es, "calcium channels"@en ;
  a ns0:Chemical, skos:Concept ;
  skos:related nalt:286434 .

nalt:2518
  skos:prefLabel "acetilcolina"@es, "acetylcholine"@en ;
  a ns0:Chemical, skos:Concept ;
  skos:related nalt:286434 .