@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .

nalt:329078
  a skos:Concept, <https://lod.nal.usda.gov/naltv#Topic> ;
  skos:inScheme <https://lod.nal.usda.gov/nalt> ;
  skos:definition nalt:329078_def ;
  skos:broader nalt:42571 ;
  skos:altLabel "CRISPR/Cas9 system"@en ;
  dc:modified "2020-08-10"^^xsd:date ;
  skos:hiddenLabel "CRISPR/Cas9"@en, "CRISPR system"@en, "CRISPR-Cas"@en, "CRISPR/Cas9-mediated"@en, "CRISPR-Cas-based"@en, "CRISPR-Cas9"@en, "CRISPR-Cas-mediated"@en ;
  dc:created "2019-03-25"^^xsd:date ;
  skos:related nalt:105992, nalt:329081, nalt:298032, nalt:318236 ;
  skos:prefLabel "sistemas CRISPR-Cas"@es, "CRISPR-Cas systems"@en ;
  ns0:marc001previous "93684" ;
  ns0:marc001 "9813982863900041" .

nalt:318236
  skos:prefLabel "proteínas asociadas a CRISPR"@es, "CRISPR-associated proteins"@en ;
  a ns0:Chemical, skos:Concept ;
  skos:related nalt:329078 .

ns0:Topic
  rdfs:label "Topic"@en ;
  a owl:Class .

nalt:105992
  skos:prefLabel "inmunidad adaptativa"@es, "adaptive immunity"@en ;
  a ns0:Topic, skos:Concept ;
  skos:related nalt:329078 .

nalt:42571
  skos:prefLabel "silenciamiento genético"@es, "gene silencing"@en ;
  a ns0:Topic, skos:Concept ;
  skos:narrower nalt:329078 .

nalt:329081
  skos:prefLabel "CRISPR proteína asociada 9"@es, "CRISPR-associated endonuclease 9"@en ;
  a ns0:Chemical, skos:Concept ;
  skos:related nalt:329078 .

<https://lod.nal.usda.gov/nalt>
  rdfs:label "NALT Full"@en ;
  a skos:ConceptScheme .

nalt:329078_def
  rdf:value "Mecanismos de defensa antivírica adaptables en arqueas y bacterias, basados en secuencias de repetición de ADN denominadas “repeticiones palindrómicas cortas agrupadas y regularmente interespaciadas” (elementos CRISPR) que funcionan en combinación con proteínas asociadas a CRISPR (proteínas Cas). Se han distinguido varios tipos, incluidos los tipos I, II y III, de acuerdo con motivos firma de proteínas asociadas a CRISPR."@es, "Adaptive antiviral defense mechanisms, in archaea and bacteria, based on DNA repeat arrays called Clustered regularly interspaced short palindromic repeats (CRISPR elements) that function in conjunction with CRISPR-associated proteins (Cas proteins). Several types have been distinguished, including Type I, Type II, and Type III, based on signature motifs of CRISPR-associated proteins."@en ;
  dc:source "Medical Subject Headings" ;
  a ns0:Definition .

nalt:298032
  skos:prefLabel "edición de genes"@es, "gene editing"@en ;
  a ns0:Topic, skos:Concept ;
  skos:related nalt:329078 .