@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .

nalt:332174
  skos:prefLabel "difteria"@es, "diphtheria"@en ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  skos:related nalt:332175 .

<https://lod.nal.usda.gov/naltv#Chemical>
  rdfs:label "Chemical"@en ;
  a owl:Class .

nalt:14706
  skos:prefLabel "Corynebacterium diphtheriae"@es, "Corynebacterium diphtheriae"@en ;
  a <https://lod.nal.usda.gov/naltv#Organism>, skos:Concept ;
  skos:related nalt:332175 .

nalt:332175
  a <https://lod.nal.usda.gov/naltv#Chemical>, skos:Concept ;
  skos:hiddenLabel "diphtheria-toxin"@en, "diphtheria toxins"@en ;
  skos:prefLabel "toxina diftérica"@es, "diphtheria toxin"@en ;
  dc:created "2019-07-10"^^xsd:date ;
  ns0:marc001 "9813985745200041" ;
  skos:related nalt:332174, nalt:14706 ;
  skos:definition nalt:332175_def ;
  skos:inScheme <https://lod.nal.usda.gov/nalt> ;
  ns0:marc001previous "93745" ;
  skos:broader nalt:15201 ;
  dc:modified "2019-11-25"^^xsd:date .

<https://lod.nal.usda.gov/nalt>
  rdfs:label "NALT Full"@en ;
  a skos:ConceptScheme .

nalt:332175_def
  rdf:value "Polipéptido de ADP ribosilación, producido por el bacilo Corynebacterium diphtheriae, que causa los síntomas de la difteria. Se puede dividir en dos dominios desiguales: el más pequeño, el dominio catalítico A, que constituye la porción letal y contiene mono (ADP ribosa) transferasas, transfiere la ADP ribosa al factor 2 de elongación peptídica, inhibiendo la síntesis proteica; el más grande, el dominio B, es necesario para entrar en las células."@es, "An ADP-ribosylating polypeptide produced by Corynebacterium diphtheriae that causes the signs and symptoms of diphtheria. It can be broken into two unequal domains: the smaller, catalytic A domain is the lethal moiety and contains mono(ADP-ribose) transferases which transfers ADP ribose to peptide elongation factor 2 thereby inhibiting protein synthesis; and the larger B domain that is needed for entry into cells."@en ;
  dc:source "Medical Subject Headings" ;
  a ns0:Definition .

nalt:15201
  skos:prefLabel "toxinas bacterianas"@es, "bacterial toxins"@en ;
  a ns0:Chemical, skos:Concept ;
  skos:narrower nalt:332175 .

