@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .

<https://lod.nal.usda.gov/naltv#Topic>
  rdfs:label "Topic"@en ;
  a owl:Class .

nalt:34248
  skos:prefLabel "dedos de zinc"@es, "zinc finger motif"@en ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  skos:narrower nalt:333337 .

nalt:333337
  dc:created "2019-08-26"^^xsd:date ;
  skos:definition nalt:333337_def ;
  skos:prefLabel "dominios de dedo RING"@es, "RING finger domains"@en ;
  skos:broader nalt:34248 ;
  skos:hiddenLabel "RING-finger"@en, "RING finger"@en ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  ns0:marc001previous "94584" ;
  skos:altLabel "RING finger motifs"@en, "RING (Really Interesting New Gene) finger domains"@en ;
  ns0:marc001 "9813981906100041" ;
  dc:modified "2019-11-25"^^xsd:date ;
  skos:inScheme <https://lod.nal.usda.gov/nalt> .

<https://lod.nal.usda.gov/nalt>
  rdfs:label "NALT Full"@en ;
  a skos:ConceptScheme .

nalt:333337_def
  rdf:value "Dominio de unión al cinc, definido por la secuencia cisteína-X2-cisteína-X (9-39)-cisteína-X (l-3)-His-X (2-3)-cisteína-X2-cisteína-X (4-48)-cisteína-X2-cisteína, donde X es cualquier aminoácido. El motivo dedo RING se une a dos átomos de cinc, cada uno de los cuales se liga de forma tetraédrica mediante cuatro cisteínas o tres cisteínas y una histidina. Además, el motivo, que da forma a una estructura unitaria con una región central, se encuentra en muchas proteínas que toman parte en interacciones proteína-proteína. La sigla RING significa really interesting new gene (nuevo gen realmente interesante)."@es, "A zinc-binding domain defined by the sequence Cysteine-X2-Cysteine-X(9-39)-Cysteine-X(l-3)-His-X(2-3)-Cysteine-X2-Cysteine -X(4-48)-Cysteine-X2-Cysteine, where X is any amino acid. The RING finger motif binds two atoms of zinc, with each zinc atom ligated tetrahedrally by either four cysteines or three cysteines and a histidine. The motif also forms into a unitary structure with a central cross-brace region and is found in many proteins that are involved in protein-protein interactions. The acronym RING stands for Really Interesting New Gene."@en ;
  dc:source "Medical Subject Headings" ;
  a ns0:Definition .