@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

nalt:60701
  skos:prefLabel "relaciones cuantitativas de actividad estructural"@es, "quantitative structure-activity relationships"@en ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  skos:related nalt:335955 .

nalt:47063
  skos:prefLabel "estudios in vivo"@es, "in vivo studies"@en ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  skos:related nalt:335955 .

nalt:335955_def
  rdf:value "Enfoque en el que se utilizan datos experimentales in vitro para predecir fenómenos in vivo, incluidas concentraciones (p. ej., toxicocinética) y efectos (p. ej., toxicodinámica)."@es, "In vitro to in vivo extrapolation (IVIVE) can be broadly defined as an approach utilizing in vitro experimental data to predict in vivo phenomena, including concentrations (e.g., toxicokinetics [TK]) and effects (e.g., toxicodynamics)."@en ;
  dc:source "US, Environmental Protection Agency" ;
  a <https://lod.nal.usda.gov/naltv#Definition> .

nalt:65620
  skos:prefLabel "pruebas de toxicidad"@es, "toxicity testing"@en ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  skos:related nalt:335955 .

nalt:335955
  skos:hiddenLabel "in-vitro to in vivo extrapolation"@en, "in-vitro to in-vivo extrapolation"@en, "IVIVE"@en, "in-vitro to in-vivo extrapolations"@en ;
  dc:modified "2020-10-29"^^xsd:date ;
  skos:inScheme <https://lod.nal.usda.gov/nalt> ;
  dc:created "2020-02-06"^^xsd:date ;
  skos:broader nalt:34395, nalt:8468 ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  skos:related nalt:65620, nalt:47063, nalt:47062, nalt:60701 ;
  skos:altLabel "IVIVE (in vitro to in vivo extrapolation)"@en ;
  skos:prefLabel "extrapolación in vitro a in vivo"@es, "in vitro to in vivo extrapolation"@en ;
  skos:definition nalt:335955_def ;
  ns0:marc001 "95105" .

ns0:Topic
  rdfs:label "Topic"@en ;
  a owl:Class .

nalt:47062
  skos:prefLabel "estudios in vitro"@es, "in vitro studies"@en ;
  a ns0:Topic, skos:Concept ;
  skos:related nalt:335955 .

nalt:8468
  skos:prefLabel "métodos analíticos"@es, "analytical methods"@en ;
  a ns0:Topic, skos:Concept ;
  skos:narrower nalt:335955 .

<https://lod.nal.usda.gov/nalt>
  rdfs:label "NALT Full"@en ;
  a skos:ConceptScheme .

nalt:34395
  skos:prefLabel "respuesta a la dosis"@es, "dose response"@en ;
  a ns0:Topic, skos:Concept ;
  skos:narrower nalt:335955 .