@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .

nalt:341523_def
  rdf:value "Gran familia de glicoproteínas secretadas que cumplen roles esenciales en el desarrollo embrionario y fetal, así como en el mantenimiento de los tejidos. Se unen a receptores Frizzled y actúan como factores de proteínas paracrinas para iniciar una variedad de vías de transducción de señales. La vía de señalización wtn canónica estabiliza el coactivador transcripcional betacatenina."@es, "Wnt proteins are a large family of secreted glycoproteins that play essential roles in embryonic and fetal development, and tissue maintenance. They bind to frizzled receptors and act as paracrine protein factors to initiate a variety of signal transduction pathways. The canonical wnt signaling pathway stabilizes the transcriptional coactivator beta catenin."@en ;
  dc:source "Medical Subject Headings" ;
  a <https://lod.nal.usda.gov/naltv#Definition> .

nalt:3937
  skos:prefLabel "factores de crecimiento"@es, "growth factors"@en ;
  a <https://lod.nal.usda.gov/naltv#Chemical>, skos:Concept ;
  skos:narrower nalt:341523 .

<https://lod.nal.usda.gov/naltv#Chemical>
  rdfs:label "Chemical"@en ;
  a owl:Class .

nalt:341523
  skos:hiddenLabel "wnt9"@en, "wnt1"@en, "wingless type protein"@en, "wnt-1"@en, "wnt13"@en, "wnt-8"@en, "wnt-14"@en, "wnt5"@en, "wnt3a"@en, "wnt10"@en, "wnt-5"@en, "wnt15"@en, "wnt2"@en, "wnt-2"@en, "wnt-3a"@en, "wnt-5a"@en, "wnt14"@en, "wnt-10"@en, "wnt-9"@en, "wnt-15"@en, "wnt6"@en, "wnt11"@en, "wnt-6"@en, "wnt16"@en, "wnt-12"@en, "wnt3"@en, "wnt-3"@en, "wnt8"@en, "wnt-11"@en, "wnt-16"@en, "wnt7"@en, "wnt12"@en, "wnt-7"@en, "wnt-13"@en, "wnt4"@en, "wnt-4"@en ;
  skos:prefLabel "wnt proteins"@en, "proteínas wnt"@es ;
  skos:broader nalt:12715, nalt:3937 ;
  a skos:Concept, <https://lod.nal.usda.gov/naltv#Chemical> ;
  skos:altLabel "wnt factors"@en, "wingless type proteins"@en ;
  dc:modified "2020-10-29"^^xsd:date ;
  skos:definition nalt:341523_def ;
  skos:inScheme <https://lod.nal.usda.gov/nalt> ;
  dc:created "2020-07-20"^^xsd:date ;
  ns0:marc001 "95710" .

nalt:12715
  skos:prefLabel "glicoproteínas"@es, "glycoproteins"@en ;
  a ns0:Chemical, skos:Concept ;
  skos:narrower nalt:341523 .

<https://lod.nal.usda.gov/nalt>
  rdfs:label "NALT Full"@en ;
  a skos:ConceptScheme .