@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .

nalt:262750
  skos:prefLabel "etopósido"@es, "etoposide"@en ;
  a <https://lod.nal.usda.gov/naltv#Chemical>, skos:Concept ;
  skos:related nalt:34181 .

nalt:15974
  skos:prefLabel "reparación de ADN"@es, "DNA repair"@en ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  skos:related nalt:34181 .

nalt:7772
  skos:prefLabel "genética molecular"@es, "molecular genetics"@en ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  skos:narrower nalt:34181 .

nalt:7777
  skos:prefLabel "mutación"@es, "mutation"@en ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  skos:related nalt:34181 .

nalt:291475
  skos:prefLabel "ensayo cometa"@es, "comet assay"@en ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  skos:related nalt:34181 .

nalt:34181
  skos:hiddenLabel "double-strand cleavage"@en, "DNA strand break"@en, "double strand breaks"@en, "DNA-damage"@en, "DNA scission"@en, "DNA lessions"@en, "DNA damaging"@en, "DNA double-strand breaks"@en, "DNA lesion"@en, "single-stranded DNA break"@en, "DNA strand breaks"@en, "DNA break"@en, "DNA breakage"@en, "DNA cleavage"@en, "DNA damages"@en, "DNA lesions"@en, "DNA breaks"@en, "excision of damaged DNA"@en, "DNA double-strand breakage"@en, "double stand breaks"@en, "single-stranded DNA breaks"@en ;
  skos:exactMatch <http://id.loc.gov/authorities/subjects/sh88006186>, <http://id.agrisemantics.org/gacs/C7740> ;
  ns0:marc001 "12385" ;
  skos:inScheme <https://lod.nal.usda.gov/nalt-core>, <https://lod.nal.usda.gov/nalt> ;
  skos:related nalt:34182, nalt:122403, nalt:15974, nalt:291475, nalt:262750, nalt:11246, nalt:7777 ;
  skos:broader nalt:7772 ;
  skos:altLabel "DNA injury"@en ;
  a skos:Concept, ns0:Topic ;
  skos:definition nalt:34181_def ;
  skos:prefLabel "DNA damage"@en, "daño al ADN"@es ;
  dc:modified "2018-10-11"^^xsd:date ;
  dc:created "2006-01-19"^^xsd:date .

nalt:11246
  skos:prefLabel "fragmentación de ADN"@es, "DNA fragmentation"@en ;
  a ns0:Topic, skos:Concept ;
  skos:related nalt:34181 .

ns0:Topic
  rdfs:label "Topic"@en ;
  a owl:Class .

nalt:122403
  skos:prefLabel "mutágenos"@es, "mutagens"@en ;
  a ns0:Chemical, skos:Concept ;
  skos:related nalt:34181 .

nalt:34181_def
  rdf:value "Daño producido por medicamentos o radiación al ADN que producen anormalidades en su conformación de doble hélice."@es, "Injuries to DNA that introduce deviations from its normal, intact structure and which may, if left unrepaired, result in a mutation or a block of DNA replication. These deviations may be caused by physical or chemical agents and occur by natural or unnatural, introduced circumstances. They include the introduction of illegitimate bases during replication or by deamination or other modification of bases; the loss of a base from the DNA backbone leaving an abasic site; single-strand breaks; double strand breaks; and intrastrand (pyrimidine dimers) or interstrand crosslinking. Damage can often be repaired. If the damage is extensive, it can induce apoptosis."@en ;
  dc:source "Medical Subject Headings 2012" ;
  a ns0:Definition .

<https://lod.nal.usda.gov/nalt>
  rdfs:label "NALT Full"@en ;
  a skos:ConceptScheme .

nalt:34182
  skos:prefLabel "genotoxicidad"@es, "genotoxicity"@en ;
  a ns0:Topic, skos:Concept ;
  skos:related nalt:34181 .