@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .

nalt:7759
  skos:prefLabel "dominios de unión al ADN"@es, "DNA-binding domains"@en ;
  a <https://lod.nal.usda.gov/naltv#Chemical>, skos:Concept ;
  skos:narrower nalt:34247 .

nalt:34247
  dc:created "2006-01-19"^^xsd:date ;
  skos:broader nalt:7759 ;
  skos:inScheme <https://lod.nal.usda.gov/nalt> ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  skos:hiddenLabel "leucine-zipper"@en ;
  dc:modified "2013-01-14"^^xsd:date ;
  skos:prefLabel "leucine zipper"@en, "leucina zipper"@es ;
  skos:definition nalt:34247_def ;
  ns0:marc001 "21210" .

ns0:Topic
  rdfs:label "Topic"@en ;
  a owl:Class .

<https://lod.nal.usda.gov/nalt>
  rdfs:label "NALT Full"@en ;
  a skos:ConceptScheme .

nalt:34247_def
  rdf:value "Motivos que se unen al ADN formados por dos alfa hélices que se entrelazan durante 8 giros en una espiral enrollada y luego se bifurcan para formar unas estructuras en forma de Y. Las leucinas que ocurren en repeticiones heptádicas terminan en los mismos lados de las hélices y son adyacentes unas a otras en el tronco de la Y (la región \"zipper\"). Los residuos que se unen al ADN se encuentran en la región bifurcada de la Y."@es, "DNA-binding motifs formed from two alpha-helixes which intertwine for about eight turns into a coiled coil and then bifurcate to form Y shaped structures. Leucines occurring in heptad repeats end up on the same sides of the helixes and are adjacent to each other in the stem of the Y (the \"zipper\" region). The DNA-binding residues are located in the bifurcated region of the Y."@en ;
  dc:source "Medical Subject Headings" ;
  a ns0:Definition .

