@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .

nalt:34640_def
  rdf:value "Mecanismo dinámico y cinético de sustancias exógenas y absorción, adsorción, biotransformación, distribución, liberación, transporte, ingestión y eliminación de medicamentos como función de dosificación, extensión y tasa de procesos metabólicos. Incluye a la toxicocinética, los mecanismos farmacocinéticos de los efectos tóxicos de una sustancia."@es, "Dynamic and kinetic mechanisms of exogenous chemical and drug absorption; biological transport; tissue distribution; biotransformation; elimination; and toxicology as a function of dosage, and rate of metabolism. It includes toxicokinetics, the pharmacokinetic mechanism of the toxic effects of a substance. ADME and ADMET are short- hand abbreviations for absorption, distribution, metabolism, elimination and toxicology."@en ;
  dc:source "Medical Subject Headings 2012" ;
  a <https://lod.nal.usda.gov/naltv#Definition> .

nalt:313430
  skos:prefLabel "diseño de fármacos"@es, "drug design"@en ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  skos:related nalt:34640 .

nalt:35791
  skos:prefLabel "toxicología"@es, "toxicology"@en ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  skos:narrower nalt:34640 .

nalt:88549
  skos:prefLabel "farmacodinámica"@es, "pharmacodynamics"@en ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  skos:related nalt:34640 .

<https://lod.nal.usda.gov/naltv#Topic>
  rdfs:label "Topic"@en ;
  a owl:Class .

nalt:34993
  skos:prefLabel "cinética"@es, "kinetics"@en ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  skos:related nalt:34640 .

nalt:192533
  skos:prefLabel "semivida biológica"@es, "biological half-life"@en ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  skos:broader nalt:34640 .

nalt:34640
  skos:exactMatch <http://aims.fao.org/aos/agrovoc/c_13280>, <http://id.loc.gov/authorities/subjects/sh00006940>, <http://id.cabi.org/cabt/88429>, <http://id.loc.gov/authorities/subjects/sh85100597>, <http://id.agrisemantics.org/gacs/C3177> ;
  skos:hiddenLabel "absorption of the drugs"@en, "pharmacodynamic parameters"@en, "pharmacokinetic analyses"@en, "absorption drugs"@en, "biopharmaceutical properties"@en, "disposition kinetics"@en, "penetration kinetics"@en, "pharmacodynamic parameter"@en, "absorption of a drug"@en, "toxicokinetic parameters"@en, "toxicokinetic differences"@en, "bio-pharmaceutical properties"@en, "plasma kinetics"@en, "bioequivalence"@en, "elimination kinetics"@en, "absorption of the drug"@en, "pharmacokinetic"@en, "pharmacokinetic analysis"@en, "toxicokinetic profile"@en ;
  skos:related nalt:313430, nalt:34639, nalt:34993, nalt:238256, nalt:88549 ;
  skos:inScheme <https://lod.nal.usda.gov/nalt>, <https://lod.nal.usda.gov/nalt-core>, <https://lod.nal.usda.gov/nalt-awic> ;
  skos:narrower nalt:192533 ;
  skos:altLabel "drug metabolism"@en, "drug biotransformation"@en, "drug absorption"@en, "toxicokinetics"@en, "drug kinetics"@en ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  dc:created "2006-01-19"^^xsd:date ;
  skos:closeMatch <http://id.loc.gov/authorities/subjects/sh85039737> ;
  ns0:marc001 "28036" ;
  skos:prefLabel "pharmacokinetics"@en, "farmacocinética"@es ;
  skos:broader nalt:35791, nalt:24572, nalt:8301 ;
  dc:modified "2020-01-17"^^xsd:date ;
  skos:definition nalt:34640_def .

<https://lod.nal.usda.gov/nalt>
  rdfs:label "NALT Full"@en ;
  a skos:ConceptScheme .

nalt:34639
  skos:prefLabel "excreción de medicamentos"@es, "drug excretion"@en ;
  a ns0:Topic, skos:Concept ;
  skos:related nalt:34640 .

nalt:24572
  skos:prefLabel "farmacología"@es, "pharmacology"@en ;
  a ns0:Topic, skos:Concept ;
  skos:narrower nalt:34640 .

nalt:238256
  skos:prefLabel "farmacometría"@es, "pharmacometrics"@en ;
  a ns0:Topic, skos:Concept ;
  skos:related nalt:34640 .

nalt:8301
  skos:prefLabel "metabolismo"@es, "metabolism"@en ;
  a ns0:Topic, skos:Concept ;
  skos:narrower nalt:34640 .