@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .

nalt:4368_def
  rdf:value "Proteínas de la superficie celular que se unen a la epinefrina y/o norepinefrina con alta afinidad y que generan cambios intracelulares. Sus dos clases principales, la alfa y la beta, se diferenciaron originalmente por sus actividades celulares; sin embargo, en la actualidad se distinguen por su afinidad relativa por ligandos sintéticos característicos. Además, se pueden clasificar de acuerdo con los subtipos de proteínas G con los que se unen; en esta disposición no se realiza la distinción alfa-beta."@es, "Cell-surface proteins that bind epinephrine and/or norepinephrine with high affinity and trigger intracellular changes. The two major classes of adrenergic receptors, alpha and beta, were originally discriminated based on their cellular actions but now are distinguished by their relative affinity for characteristic synthetic ligands. Adrenergic receptors may also be classified according to the subtypes of G-proteins with which they bind; this scheme does not respect the alpha-beta distinction."@en ;
  dc:source "Medical Subject Headings" ;
  a <https://lod.nal.usda.gov/naltv#Definition> .

nalt:223314
  skos:prefLabel "receptores de catecolamina"@es, "catecholamine receptors"@en ;
  a <https://lod.nal.usda.gov/naltv#Chemical>, skos:Concept ;
  skos:narrower nalt:4368 .

nalt:223382
  skos:prefLabel "receptores de epinefrina"@es, "epinephrine receptors"@en ;
  a <https://lod.nal.usda.gov/naltv#Chemical>, skos:Concept ;
  skos:broader nalt:4368 .

nalt:4359
  skos:prefLabel "agentes adrenérgicos"@es, "adrenergic agents"@en ;
  a <https://lod.nal.usda.gov/naltv#Chemical>, skos:Concept ;
  skos:related nalt:4368 .

<https://lod.nal.usda.gov/naltv#Chemical>
  rdfs:label "Chemical"@en ;
  a owl:Class .

nalt:4368
  a <https://lod.nal.usda.gov/naltv#Chemical>, skos:Concept ;
  skos:narrower nalt:255340, nalt:223382, nalt:255358 ;
  dc:created "2006-01-19"^^xsd:date ;
  ns0:marc001 "1020" ;
  skos:related nalt:218582, nalt:4359 ;
  skos:inScheme <https://lod.nal.usda.gov/nalt> ;
  skos:hiddenLabel "adrenergic receptor"@en, "adrenergic-receptors"@en, "adrenoceptor"@en ;
  skos:prefLabel "adrenergic receptors"@en, "receptores adrenérgicos"@es ;
  dc:modified "2019-12-16"^^xsd:date ;
  skos:closeMatch <http://id.loc.gov/authorities/subjects/sh85001011> ;
  skos:broader nalt:223314 ;
  skos:altLabel "adrenoceptors"@en ;
  skos:definition nalt:4368_def .

nalt:255358
  skos:prefLabel "receptores adrenérgicos beta"@es, "beta adrenergic receptors"@en ;
  a ns0:Chemical, skos:Concept ;
  skos:broader nalt:4368 .

nalt:255340
  skos:prefLabel "receptores adrenérgicos alfa"@es, "alpha adrenergic receptors"@en ;
  a ns0:Chemical, skos:Concept ;
  skos:broader nalt:4368 .

nalt:218582
  skos:prefLabel "fenilpropanolamina"@es, "phenylpropanolamine"@en ;
  a ns0:Chemical, skos:Concept ;
  skos:related nalt:4368 .

<https://lod.nal.usda.gov/nalt>
  rdfs:label "NALT Full"@en ;
  a skos:ConceptScheme .