@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .

nalt:57094482
  skos:inScheme <https://lod.nal.usda.gov/nalt>, <https://lod.nal.usda.gov/nalt-awic> ;
  skos:broader nalt:65620 ;
  ns0:marc001 "57094482" ;
  skos:definition nalt:57094482_def ;
  a skos:Concept ;
  dc:modified "2024-05-04"^^xsd:date ;
  skos:prefLabel "neutral red uptake assay (NRU)"@en, "ensayo de captación de rojo neutro (NRU)"@es ;
  dc:created "2023-04-03"^^xsd:date .

nalt:57094482_def
  rdf:value "Enfoque basado en células in vitro que evalúa la captación celular de un colorante en presencia de una sustancia determinada y que se utiliza para calcular la citotoxicidad basal. En EE. UU. y Europa se validó como método alternativo en el ámbito de la toxicología."@es, "An in-vitro cell-based approach that assesses the cellular uptake of a dye in the presence of a particular substance and is used to assess basal cytotoxicity. It has been validated in the U.S. and Europe as an alternative method in toxicology."@en ;
  dc:source "Based upon Neutral red uptake for starting doses for acute oral toxicity [NRU Cytotoxicity (2003). TM2003-01 (US). ICCVAM/NICEATM (US). TSAR - Tracking System for Alternative methods towards Regulatory acceptance. European Commission website. Accessed 9/21/2022." ;
  a ns0:Definition .

<https://lod.nal.usda.gov/nalt>
  rdfs:label "NALT Full"@en ;
  a skos:ConceptScheme .

nalt:65620
  skos:prefLabel "pruebas de toxicidad"@es, "toxicity testing"@en ;
  a ns0:Topic, skos:Concept ;
  skos:narrower nalt:57094482 .