@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

nalt:61571_def
  rdf:value "Antibiótico semisintético producido a partir de Streptomyces mediterranei. Tiene un amplio espectro antibacteriano, incluyendo la actividad contra diversas formas de Mycobacterium. En organismos susceptibles, éste inhibe la actividad del ADN dependiente de la ARN polimerasa mediante la formación de un complejo estable con la enzima. Por lo tanto, suprime la iniciación de la síntesis de ARN. La rifampicina es bactericida y actúa sobre ambos organismos intracelulares y extracelulares."@es, "A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms."@en ;
  dc:source "Medical Subject Headings 2011" ;
  a <https://lod.nal.usda.gov/naltv#Definition> .

nalt:61571
  skos:broader nalt:10208 ;
  skos:hiddenLabel "rifampicins"@en ;
  ns0:marc001 "32233" ;
  dc:modified "2015-06-15"^^xsd:date ;
  skos:inScheme <https://lod.nal.usda.gov/nalt-core>, <https://lod.nal.usda.gov/nalt> ;
  skos:prefLabel "rifampicina"@es, "rifampicin"@en ;
  skos:altLabel "rimactan"@en, "rifampin"@en, "rifadin"@en ;
  skos:closeMatch <http://id.loc.gov/authorities/subjects/sh87003747> ;
  skos:definition nalt:61571_def ;
  skos:exactMatch <http://id.cabi.org/cabt/101800>, <http://id.agrisemantics.org/gacs/C10811> ;
  dc:created "2006-01-19"^^xsd:date ;
  a ns0:Chemical, skos:Concept .

ns0:Chemical
  rdfs:label "Chemical"@en ;
  a owl:Class .

nalt:10208
  skos:prefLabel "rifamicinas"@es, "rifamycins"@en ;
  a ns0:Chemical, skos:Concept ;
  skos:narrower nalt:61571 .

<https://lod.nal.usda.gov/nalt>
  rdfs:label "NALT Full"@en ;
  a skos:ConceptScheme .