@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

nalt:278705
  skos:prefLabel "mutación de pérdida de función"@es, "loss-of-function mutation"@en ;
  a <https://lod.nal.usda.gov/naltv#Topic>, skos:Concept ;
  skos:broader nalt:7777 .

nalt:7777
  skos:definition nalt:7777_def ;
  skos:narrower nalt:332871, nalt:53145, nalt:234509, nalt:41398, nalt:17293, nalt:10457, nalt:322730, nalt:132647, nalt:53832, nalt:278704, nalt:200052, nalt:7778, nalt:15971, nalt:7776, nalt:322719, nalt:324468, nalt:132641, nalt:278705 ;
  skos:inScheme <https://lod.nal.usda.gov/nalt>, <https://lod.nal.usda.gov/nalt-core> ;
  skos:altLabel "mutations"@en ;
  skos:related nalt:302272, nalt:217222, nalt:326266, nalt:34181, nalt:2165, nalt:301548, nalt:226519, nalt:332864, nalt:53830, nalt:122403, nalt:14079 ;
  skos:prefLabel "mutación"@es, "mutation"@en ;
  dc:created "2006-01-19"^^xsd:date ;
  a skos:Concept, <https://lod.nal.usda.gov/naltv#Topic> ;
  skos:hiddenLabel "mutation landscape"@en, "mutational landscape"@en, "mutational landscapes"@en, "mutation landscapes"@en ;
  ns0:marc001 "24317" ;
  skos:exactMatch <http://id.agrisemantics.org/gacs/C869>, <http://aims.fao.org/aos/agrovoc/c_5014>, <http://id.loc.gov/authorities/subjects/sh00006798>, <http://id.cabi.org/cabt/76089> ;
  dc:modified "2019-08-06"^^xsd:date ;
  skos:broader nalt:7772 .

nalt:14079
  skos:prefLabel "mutantes"@es, "mutants"@en ;
  a ns0:Topic, skos:Concept ;
  skos:related nalt:7777 .

nalt:122403
  skos:prefLabel "mutágenos"@es, "mutagens"@en ;
  a ns0:Chemical, skos:Concept ;
  skos:related nalt:7777 .

nalt:322719
  skos:prefLabel "mutación espontánea"@es, "spontaneous mutation"@en ;
  a ns0:Topic, skos:Concept ;
  skos:broader nalt:7777 .

nalt:278704
  skos:prefLabel "mutación de ganancia de función"@es, "gain-of-function mutation"@en ;
  a ns0:Topic, skos:Concept ;
  skos:broader nalt:7777 .

<https://lod.nal.usda.gov/nalt>
  rdfs:label "NALT Full"@en ;
  a skos:ConceptScheme .

nalt:7776
  skos:prefLabel "sustitución de aminoácidos"@es, "amino acid substitution"@en ;
  a ns0:Topic, skos:Concept ;
  skos:broader nalt:7777 .

nalt:7777_def
  rdf:value "Cualquier cambio en el material genético que puede detectarse y heredarse, que no es causado por segregación o recombinación genética y que se transmite a las células hijas y las generaciones siguientes, a menos que sea un factor letal dominante."@es, "Any detectable and heritable change in the genetic material that causes a change in the genotype and which is transmitted to daughter cells and to succeeding generations."@en ;
  dc:source "Medical Subject Headings 2012" ;
  a ns0:Definition .

nalt:332871
  skos:prefLabel "inestabilidad genética"@es, "genetic instability"@en ;
  a ns0:Topic, skos:Concept ;
  skos:broader nalt:7777 .

nalt:302272
  skos:prefLabel "equilibrio genético"@es, "genetic equilibrium"@en ;
  a ns0:Topic, skos:Concept ;
  skos:related nalt:7777 .

nalt:217222
  skos:prefLabel "biogénesis"@es, "biogenesis"@en ;
  a ns0:Topic, skos:Concept ;
  skos:related nalt:7777 .

nalt:132641
  skos:prefLabel "mutación inducida"@es, "induced mutation"@en ;
  a ns0:Topic, skos:Concept ;
  skos:broader nalt:7777 .

nalt:10457
  skos:prefLabel "mutagénesis"@es, "mutagenesis"@en ;
  a ns0:Topic, skos:Concept ;
  skos:broader nalt:7777 .

nalt:132647
  skos:prefLabel "mutación somática"@es, "somatic mutation"@en ;
  a ns0:Topic, skos:Concept ;
  skos:broader nalt:7777 .

nalt:234509
  skos:prefLabel "eliminación de secuencia"@es, "sequence deletion"@en ;
  a ns0:Topic, skos:Concept ;
  skos:broader nalt:7777 .

nalt:53832
  skos:prefLabel "mutación sin sentido"@es, "nonsense mutation"@en ;
  a ns0:Topic, skos:Concept ;
  skos:broader nalt:7777 .

nalt:322730
  skos:prefLabel "acumulación de mutaciones"@es, "mutation accumulation"@en ;
  a ns0:Topic, skos:Concept ;
  skos:broader nalt:7777 .

nalt:301548
  skos:prefLabel "análisis mutacional"@es, "mutational analysis"@en ;
  a ns0:Topic, skos:Concept ;
  skos:related nalt:7777 .

nalt:41398
  skos:prefLabel "desplazamiento del marco de lectura"@es, "frameshift mutation"@en ;
  a ns0:Topic, skos:Concept ;
  skos:broader nalt:7777 .

nalt:326266
  skos:prefLabel "genética inversa"@es, "reverse genetics"@en ;
  a ns0:Topic, skos:Concept ;
  skos:related nalt:7777 .

nalt:34181
  skos:prefLabel "daño al ADN"@es, "DNA damage"@en ;
  a ns0:Topic, skos:Concept ;
  skos:related nalt:7777 .

nalt:324468
  skos:prefLabel "desequilibrio alélico"@es, "allelic imbalance"@en ;
  a ns0:Topic, skos:Concept ;
  skos:broader nalt:7777 .

nalt:17293
  skos:prefLabel "polimorfismo genético"@es, "genetic polymorphism"@en ;
  a ns0:Topic, skos:Concept ;
  skos:broader nalt:7777 .

nalt:53830
  skos:prefLabel "mutagenicidad"@es, "mutagenicity"@en ;
  a ns0:Topic, skos:Concept ;
  skos:related nalt:7777 .

nalt:226519
  skos:prefLabel "ensayo de amplificación de mutación desajustada"@es, "mismatch amplification mutation assay"@en ;
  a ns0:Topic, skos:Concept ;
  skos:related nalt:7777 .

nalt:53145
  skos:prefLabel "mutación puntual"@es, "point mutation"@en ;
  a ns0:Topic, skos:Concept ;
  skos:broader nalt:7777 .

ns0:Topic
  rdfs:label "Topic"@en ;
  a owl:Class .

nalt:15971
  skos:prefLabel "disparidad de par de base"@es, "base pair mismatch"@en ;
  a ns0:Topic, skos:Concept ;
  skos:broader nalt:7777 .

nalt:7772
  skos:prefLabel "genética molecular"@es, "molecular genetics"@en ;
  a ns0:Topic, skos:Concept ;
  skos:narrower nalt:7777 .

nalt:7778
  skos:prefLabel "mutación missense"@es, "missense mutation"@en ;
  a ns0:Topic, skos:Concept ;
  skos:broader nalt:7777 .

nalt:2165
  skos:prefLabel "adaptación"@es, "evolutionary adaptation"@en ;
  a ns0:Topic, skos:Concept ;
  skos:related nalt:7777 .

nalt:332864
  skos:prefLabel "tasa de mutación"@es, "mutation rate"@en ;
  a ns0:Topic, skos:Concept ;
  skos:related nalt:7777 .

nalt:200052
  skos:prefLabel "eliminación de aminoácidos"@es, "amino acid deletion"@en ;
  a ns0:Topic, skos:Concept ;
  skos:broader nalt:7777 .