@prefix nalt: <https://lod.nal.usda.gov/nalt/> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix ns0: <https://lod.nal.usda.gov/naltv#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

nalt:59096
  skos:prefLabel "tetraclorodibenzo-p-dioxina"@es, "tetrachlorodibenzo-p-dioxin"@en ;
  a <https://lod.nal.usda.gov/naltv#Chemical>, skos:Concept ;
  skos:related nalt:335856 .

nalt:335856_def
  rdf:value "Proteínas citoplasmáticas que unen ciertos hidrocarburos de arilo, se translocan en el núcleo y activan la transcripción de segmentos particulares de ADN. Se identifican por su gran afinidad, uniéndose a varias sustancias químicas ambientales carcinógenas o teratógenas, incluidos los hidrocarburos aromáticos policíclicos que se hallan en el humo del cigarrillo, el esmog, los aminos heterocíclicos presentes en los alimentos cocidos y los hidrocarburos halogenados, incluidas las dioxinas y los policlorobifenilos. No se ha identificado ningún ligando endógeno; sin embargo, se sospecha la existencia de un mensajero natural desconocido, con una función en la diferenciación y el desarrollo celular."@es, "Cytoplasmic proteins that bind certain aryl hydrocarbons, translocate to the nucleus, and activate transcription of particular DNA segments. AH receptors are identified by their high-affinity binding to several carcinogenic or teratogenic environmental chemicals including polycyclic aromatic hydrocarbons found in cigarette smoke and smog, heterocyclic amines found in cooked foods, and halogenated hydrocarbons including dioxins and polychlorinated biphenyls. No endogenous ligand has been identified, but an unknown natural messenger with a role in cell differentiation and development is suspected."@en ;
  dc:source "Medical Subject Headings" ;
  a <https://lod.nal.usda.gov/naltv#Definition> .

nalt:335856
  ns0:marc001 "95098" ;
  skos:hiddenLabel "poly-aromatic hydro-carbon receptor"@en, "TCDD-receptor"@en, "TCDD receptors"@en, "aryl-hydrocarbon receptors"@en, "poly aromatic hydrocarbon receptor"@en, "aryl-hydrocarbon receptor"@en, "dioxin receptor"@en, "polyaromatic hydrocarbon receptor"@en, "poly-aromatic hydrocarbon receptor"@en, "TCDD receptor"@en, "TCDD-receptors"@en, "dioxin-receptor"@en, "poly-aromatic hydrocarbon receptors"@en, "aryl hydrocarbon receptor"@en ;
  skos:broader nalt:335860, nalt:34250 ;
  a ns0:Chemical, skos:Concept ;
  dc:created "2020-02-03"^^xsd:date ;
  skos:altLabel "TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin) receptors"@en, "polyaromatic hydrocarbon receptors"@en, "Ah (aryl hydrocarbon) receptors"@en, "dioxin receptors"@en ;
  skos:inScheme <https://lod.nal.usda.gov/nalt> ;
  skos:related nalt:59096 ;
  skos:definition nalt:335856_def ;
  skos:prefLabel "receptores de hidrocarburos de arilo"@es, "aryl hydrocarbon receptors"@en ;
  dc:modified "2020-10-29"^^xsd:date .

nalt:335860
  skos:prefLabel "receptores nucleares huérfanos"@es, "orphan nuclear receptors"@en ;
  a ns0:Chemical, skos:Concept ;
  skos:narrower nalt:335856 .

ns0:Chemical
  rdfs:label "Chemical"@en ;
  a owl:Class .

<https://lod.nal.usda.gov/nalt>
  rdfs:label "NALT Full"@en ;
  a skos:ConceptScheme .

nalt:34250
  skos:prefLabel "factores de transcripción"@es, "transcription factors"@en ;
  a ns0:Chemical, skos:Concept ;
  skos:narrower nalt:335856 .